DHH with a pants-on-head stupid argument just because he hates the big players in tech? Must be a day ending in Y again.

The Nobel committees frequently give prizes in an area that really have more to do with other areas. Six of the last ten Nobels in Chemistry have been explicitly biology focused. Two more were materials science stuff, so maybe half chemistry. Only two were what I’d consider actual chemistry.

But this one is pretty rough. The Nobel Prize in Physics goes to setting the world’s energy reserves on fire so coked-up executives’ lines can go up and basement-dwellers can generate waifus with big tiddies. UGH

The industry standard is HPLC (high performance liquid chromatography). Those things go for tens of thousands of dollars up front, plus maintenance and consumables.

If there was a less costly way of doing it, you bet companies would have settled on that by now.

make the best decisions they can

I would recommend an HPLC and a competent analytical chemist to gather data and decide whether or not a batch is safe to consume.

This has been posted to a bunch of different communities, and I’m gonna be a stick in the mud each time.

I’m a process chemist. I do this for a living. I’ve made kilo-scale batches of pharmaceuticals at work that have gone through the regulatory process and made it into people. I went to school for ten years to do this.

This is a colossally dangerous thing.

Every time you run a chemical synthesis, you generate impurities. Slightly different temperatures, concentrations, reagent quality, and a million other things will vary the identities and concentrations of those impurities in your product.

The nature of biochemistry is that most compounds, even at very small concentrations, can have effects. Usually bad ones. So drugs have tight specs on how much of each potential impurity can be present. Usually it’s in the 0.1% range, but sometimes a lot lower.

Detection of impurities at that level cannot be done with ‘hacker’ gear in your garage. So if you do this, you’re going to be taking unknown quantities of unknown impurities.

There are trade-offs. If you’re definitely gonna die without the medicine, then the worst that can happen is you die faster, or more painfully. If it’s medicine to maintain quality of life, then you might die fast and painfully.

I’m not saying the current system is good at all. Medicine is too expensive. It shouldn’t be limited by right wing nutjobs. Those things are true. Those things require a solution.

This is not a good solution.

Unless our ability to cram delta-V into a spacecraft goes way beyond what seems possible now with chemical rockets, a trip to the moon is always gonna involve a few days of coasting through space. That’s always going to take more preparation than a transatlantic flight.

A lot of the Apollo work also got done in basically one administration (Johnson largely continued JFK’s policies). As soon as Nixon was in charge, NASA got gutted, and then they only had the resources for shuttle. Later Apollo missions got cancelled because Nixon thought the money was better spent killing more Vietnamese people.

Switching administrations means vastly changing policies, if for no other reason than the new boss hates the old boss. SLS “succeeded” (got hardware made and launched, at least) where Constellation failed partly because they buttered everyone’s bread in the right way.

HLS is dumb. SLS is dumb. But similarly to Commercial Cargo and Crew, it survived administration changes partly because NASA wasn’t directly at the helm, so the new guys didn’t just hit the big red stop button.

In the entire history of NASA, they’ve never manufactured any boosters for themselves. Redstone was from the army. Titan, also military. Saturn I and V were designed by NASA but contracted to big aircraft manufacturers as contractors. Shuttle was Boeing / Rockwell for the orbiter, ATK for the boosters. SLS is basically all the Shuttle contractors, again. (That was the point.)

I hear what you’re saying. But NASA would need to spin up an entire company from scratch to build their own rockets. That’s not what their mandate is, and it’s not what they’re good at.

It was a scan during upload to their cloud photos system. Everyone else does it on their servers, Apple was going to run the scan before so they didn’t have to ever have them. To not have images scanned before upload, a user would just not have to use their cloud photos service.

The messaging was really badly handled. They almost certainly just scan all the same photos on their servers instead now.

1. Hack together a proof of concept
2. Works well enough that management slaps a “done” sticker on it
3. Pile of hacks becomes load bearing
4. One or two dependencies change, the whole thing falls over
5. Set evenings and weekends on fire to fix it
6. Management brags about moving fast and breaking things, engineers quit and become cabbage farmers and woodworkers
7. New graduates are hired, GOTO 1

Hopefully not as a bunch of really good question posts full of mod-deleted answers.

The labrats subreddit was kinda fun. I’m a chemist, but the chemistry subreddit was overwhelmed by people asking for homework advice, showing off bad caffeine tattoos, and getting upset when they couldn’t talk about drugs or explosives.

I’m sure that whatever is causing the leak, after being shaken violently and pulling a few g’s during ascent, will get… better?

Have… have you read any of the playtest material? Like, I think they’re a bunch of dinguses too. But there are some substantial modifications in there that everyone will feel when playing.

The axe forgets, the stump remembers

You should ask, like, any woman in your life.

Yep. My little Field Notes books don’t send me notifications about emails, and I can toss them around without breaking them. And use a lot of notation and drawing methods that are very slow when typing with my thumbs.